Bioreactors and fermenters from benchtop research to production scale

Benchtop Bioreactors

250 ml – 10 L | Glass and autoclavable vessel options

For controlled laboratory-scale cul­ti­vation in micro­biology and cell culture – early R&D to method develop­ment and small-scale process work.

Start here if you need a flexible lab-scale bioreactor with strong configuration freedom and reliability.

• Fermentation and cell culture
• Single or twin-vessel configurations
• Double-wall borosilicate glass vessels
• Single-wall glass and stainless-steel vessel options

Parallel Bioreactors

2–24 vessels | Modular process development

For running multiple controlled cultivations side by side – for screening, media development to process comparison and scale-up preparation.

Start here if you need reproducible comparison across several independently controlled vessels.

• xCUBIO twin for 2 vessels
• xCUBIO multi for up to 24 vessels
• Modular supply-tower architecture
• Same vessel options as benchtop systems

Pilot-Scale Bioreactors

Stainless steel | SIP-capable scale-up systems

For moving from lab development into SIP-capable stainless-steel systems for scale-up, process characterization and pre-production work.

Start here if your process has outgrown laboratory vessels and needs stainless-steel SIP capability.

• Stainless-steel vessel design
• Steam-sterilizable bioreactor systems
• CIP depending on project scope
• Typically 2–50 L, sometimes up to 100 L

Production Bioreactors

100 L – 10,000 L+ | Production trains and sterile transfer

For production-scale bioprocesses with stainless-steel vessels, automated sterile transfer and complete seed-to-production bioreactor trains.

Start here if you need production capacity, sterile transfer or a complete reactor train.

• Stainless-steel vessels
• CIP/SIP-capable and automated transfer lines
• Complete seed-to-production trains
• Optional automated transfer sequences

Double-wall vessels

250 ml – 10 L | Universal stirred glass vessel with double-wall

The classic stirred glass bioreactor concept with shaft-driven agitation and temperature control via xCUBIO TCU or an external circulation thermostat.

Best for: Users who need a universal glass vessel concept with stable, homogeneous temperature control for fermentation and cell culture.

• Shaft-driven stirred bioreactor design
• Best and most even heat transfer
• Temperature control via xCUBIO TCU or external unit
• Universal option for fermentation and cell culture

Single-wall vessels

250 ml – 10 L | Stirred glass vessel with single wall and heating mat

A simplified stirred glass vessel concept using a flexible heating mat instead of a permanent liquid circulation loop for temperature control.

Best for: Cell-culture-oriented setups where simple handling and a dry temperature-control concept are preferred for daily operation.

• Temperature control via heating jacket
• No permanent water circulation loop
• Simpler setup and daily handling
• Often selected for cell culture applications

Stainless steel vessels

2 L – 10 L | Autoclavable stainless-steel vessel with sight glass

Autoclavable stainless-steel vessel concept with double-wall temperature control for enhanced safety, durability and higher-pressure fermentations.

Best for: Demanding microbial fermentations, higher-pressure requirements and users who need a safer alternative to glass vessels

• Robust stainless-steel vessel construction
• Double-wall temperature-control concept
• Suitable for higher-pressure fermentations
• Sight glass for cultivation process visibility

Airlift vessels

500 ml – 10 L | Airlift circulation without mechanical stirring

A specialized glass vessel concept for processes where aeration, circulation and gas–liquid contact are central to cultivation and scale-up.

Best for: Pneumatically mixed vessel concepts for aerated processes, lower mechanical shear and simplified vessel internals.

• Gas-driven circulation via airlift principle
• Aeration and mixing combined in one concept
• Suitable for shear-sensitive or gas-focused processes
• No shaft or stirring elements in the vessel

GL 45 reactor vessels

250 ml – 50 L | Low-cost bottle-based reactor concept

An economical bottle-based reactor concept with magnetic stirring and one sensor port for simple culti­vation tasks and early feasibility studies.

Best for: Cost-conscious entry-level work, simple lab work­flows and applications with limited sensor requirements.

• Bottle-based reactor concept from 250 ml to 50 L
• One sensor port
• Magnetic stirring instead of shaft drive
• Low-cost alternative for simple cultivation tasks

GLS 80 reactor vessels

250 ml – 50 L | Bottle-based reactor concept

A bottle-based reactor concept similar to GL45 reactors, but with three sensor ports for more flexible and enhanced monitoring and control.

Best for: Users who want simple bottle-based reactor handling with more sensor flexibility than GL45 allows.

• Bottle-based reactor concept from 250 ml to 50 L
• Three sensor ports
• Magnetic stirring instead of shaft drive
• More monitoring and control options than GL45

Vessels with bottom outlet

500 ml – 10 L | Bottom outlet for transfer, harvest and circulation

A specialized vessel concept with bot­tom outlet for draining, transfer and down­stream processes, with circulation options to create defined turbulence.

Best for: Processes where harvest, draining, transfer or downstream integration are part of the process strategy.

• Bottom outlet for easier draining and harvest
• Creates defined turbulence
• Designed for transfer and downstream workflows
• Supports circulation-based process concepts

Special geometry vessels

500 ml – 10 L | Adapted height-to-diameter ratios

Application-specific vessel geometries for experiments, process questions or installation constraints where standard vessel dimensions are not the best fit.

Best for: Special experiments, defined geometry requirements or vessel dimensions that must fit specific autoclave sizes.

• Supports defined geometry requirements
• Adapted vessel geometries
• Useful for special process experiments
• Designed around process or autoclave constraints