Support for running bioreactors – from preventive maintenance and spare parts to repair, consumables and modernization decisions.
Whether you operate a current xCUBIO system, a bbi-biotech bioreactor or an older installed Biostat®, B. Braun or Sartorius system, bbi-biotech helps you find the right next step for maintenance, troubleshooting, spare parts, consumables, remote support and selected documentation-related service topics.
For standard spare parts, accessories and catalogue items, the bbi-biotech shop is often the fastest route. For unclear technical cases, legacy systems, compatibility questions or service planning, send us your system details so we can review the case properly.
What do you need help with?
Maintenance
Preventive maintenance and annual service
Plan recurring technical checks and structured service support to keep running bioreactors and fermenters reliable, maintainable and ready for continued operation.
Repair
Troubleshooting and technical service cases
Discuss unexpected system behavior, damaged components, operational issues or technical faults before deciding on repair, spare parts or further assessment.
Consumables
Spare parts, accessories and lifecycle supply
Find wear parts, consumables, tubing, seals, filters, sensors, sampling accessories and vessel-side components – or ask us to identify the right item.
Documentation
Calibration, qualification and regulations
Clarify calibration certificates, IQ/OQ templates, FAT/SAT support, PQ-related topics, GAMP5 or 21 CFR Part 11 requirements according to the agreed scope.
Training
Courses, operational briefing and lectures
Support your team with system training, operational briefing, application-related courses or technical lectures for safer and more consistent bioreactor operation.
Consulting
Pre-engineering and technical clarification
Clarify requirements before a service, upgrade, retrofit or new project decision — from system feasibility and configuration to documentation, interfaces and technical scope.
Preventive maintenance and annual service
Plan service work before small technical issues become production or research interruptions. Preventive maintenance helps keep bioreactors and fermenters reliable, supportable and ready for continued operation.
For running xCUBIO systems, bbi-biotech bioreactors and selected older installed systems, bbi-biotech can discuss recurring technical checks, annual maintenance, wear-part review, sensor-related service needs and practical recommendations for continued use.
A maintenance discussion can help clarify the current condition of your system, identify parts or consumables that should be checked or replaced, and define whether the system needs a focused service visit, a broader technical review or a more structured service level.
The exact scope depends on the system, operating environment, service history, documentation requirements and the level of support required.
System condition review
A practical review of the current system condition, including visible wear, operating issues and components that may need closer technical attention.
Wear parts and consumables
Review of regularly required items such as seals, tubing, filters, sampling-related parts and other consumables that support continued operation.
Sensors, probes and calibration needs
Discussion of sensor condition, probe-related service topics, calibration requirements and certificates where needed.
Pumps, tubing and vessel-side components
Review of pumps, tubing paths, vessel-side accessories, fittings, connectors and components that are relevant for reliable operation.
Controller-related topics
Discussion of controller behavior, software-related questions, automation-related observations or remote-support options depending on system configuration.
Documentation requirements
Clarification of maintenance records, calibration certificates or qualification-related documentation that may be required for your operating environment.
If you already know your system type, controller generation, vessel size or serial number, please include this information. Photos of the system or affected components are often helpful.
Service scope for running bioreactors and fermenters
bbi-biotech focuses service support on bioreactors, fermenters and closely related components used in bioprocess operation. The exact support path depends on the system, configuration, condition and available technical information.
Core systems
xCUBIO and bbi-biotech bioreactors
Service support for current systems, including maintenance, troubleshooting, spare parts, consumables, calibration-related topics and documentation-related service needs.
Legacy systems
Biostat®, B. Braun and Sartorius systems
Support discussion for older installed stainless-steel bioreactors where service, spare parts or modernization assessment may help extend useful system life.
Selected systems
Other bioreactors after technical review
Case-by-case review of selected third-party bioreactors or fermenters, depending on system information, technical feasibility and component compatibility..
Please include the system manufacturer, model, vessel size, controller type and serial number where available. Photos of the system or affected component can help us assess the case more efficiently.
Consumables and lifecycle supply
Running bioreactors need more than occasional service visits. Reliable access to regularly required consumables, wear parts and vessel-side items helps keep systems usable across many batches and maintenance cycles.
Consumable sets
Prepared sets for xCUBIO vessels and routine replacement needs
Use ready-to-request consumable sets and wear-parts sets for xCUBIO vessels across available volumes, especially when recurring maintenance or batch-related replacement is planned.
Seals and O-rings
Gaskets, port seals and O-rings for bioreactor accessories
Request regularly required sealing components such as gaskets, O-rings, flat seals and accessory seals for headplates, ports, adapters and vessel-side assemblies.
Membranes and filters
Membranes, filters and sterile barrier-related items
Support continued operation with membranes, filters and related consumables used in sampling, inoculation, bypass, exhaust or other sterile handling points.
Tubing and hoses
Tubes, hoses and material for assembly
Request tubing, hoses, clamping components and assembly-related material for routine service work, replacement needs or system-side adjustments.
Sampling accessories
Sampling-related parts and consumables
Clarify sampling-related consumables, membranes, connectors or accessories used for manual sampling, bypass sampling or automated sampling setups.
Compatibility review
For unclear or system-specific requirements
If the required item is unclear, the system is older or compatibility needs to be checked, send us the system details before requesting catalogue items.
Request catalogue items or discuss compatibility?
Some service cases can be handled through standard catalogue items, while others need technical review before the right part or support path can be defined. Use the shop when the required item is clear – and contact bbi-biotech when compatibility, legacy systems or system-specific details need to be checked.
Request catalogue items
For known standard parts and consumables
Use the bbi-biotech shop when you already know the required catalogue item or product category. Standard spare parts, consumables, wear parts, tubing, seals, membranes, filters, O-rings, sampling accessories and xCUBIO wear-parts sets can be requested through the shop.
Items can be added to a quote request.
Discuss compatibility
For unclear, legacy or system-specific requirements
Contact bbi-biotech when the required item is unclear, the system is older, the component is not listed, or compatibility with a vessel, headplate, controller, sensor, port, adapter or legacy system needs to be checked before a technically responsible quotation is prepared.
Include photos, model details and serial number.
For spare-parts and service-related questions, you can also contact us directly at shop@bbi-biotech.com or call: +49 30 221 800 10.
Support for xCUBIO and older installed bioreactors
Current xCUBIO systems and older stainless-steel bioreactors often need different technical support paths, but the same lifecycle need: regular servicing, reliable spare-parts access and a clear maintenance concept.
xCUBIO systems
Regular servicing for current bbi-biotech automation and bioreactors
For xCUBIO systems, bbi-biotech can support preventive maintenance, regular service planning, spare parts, consumables, controller-related topics, sensor and probe discussions and documentation-related service needs.
Legacy hardware
Maintenance support for Biostat®, B. Braun and Sartorius stainless-steel bioreactors
For suitable stainless-steel Biostat®, B. Braun and Sartorius bioreactors, bbi-biotech can support hardware-related maintenance, regular servicing, spare-parts planning, consumables, vessel-side components and repair assessment.
Service agreements
Maintenance concepts and service contracts for running bioreactor systems
For running systems, bbi-biotech can discuss recurring service intervals, annual maintenance and suitable maintenance agreements depending on system type, location, operating environment and specific validation and support needs.
Repair, maintain or assess retrofit options?
Not every technical issue requires a retrofit, and not every older bioreactor needs to be replaced. bbi-biotech helps you decide whether repair, regular maintenance or an xCUBIO retrofit assessment is the most practical next step.
Calibration, documentation and qualification-related support
Some service cases require more than technical work on the bioreactor itself. bbi-biotech can discuss calibration certificates, qualification-related documentation and regulated-environment requirements according to the agreed system scope.
Calibration
Certificates and calibration-related service needs
bbi-biotech can discuss calibration certificates, sensor-related calibration topics and documentation needs connected to maintenance, service work or continued system operation.
Best used when service work must be documented, traceable or aligned with internal quality requirements.
- Calibration certificates where required
- Sensor and probe-related topics
- Service records for continued use
Qualification
IQ/OQ templates and qualification-related documentation
For suitable systems and agreed service scopes, bbi-biotech can support qualification-related documentation such as IQ/OQ templates or project-specific documentation packages.
The exact documentation scope should be defined before service, retrofit or project execution begins.
- IQ/OQ templates where applicable
- Project-specific documentation packages
- Scope clarification before execution
FAT, SAT and PQ
Support before, during and after technical acceptance
Depending on the system, project and service scope, bbi-biotech can support FAT and SAT activities and discuss PQ-related support where customer procedures require technical input.
This helps connect technical service work with customer-side acceptance and qualification workflows.
- Factory Acceptance Test for all systems
- Site Acceptance Test support after installation
- Performance Qualification-related technical input
Regulated environments
GAMP5, 21 CFR Part 11 and related requirements
For xCUBIO systems and relevant service or retrofit cases, bbi-biotech can discuss GAMP5-oriented documentation needs, audit-trail topics and 21 CFR Part 11-related automation requirements.
This is especially relevant when automation changes must remain understandable, documented and reviewable.
- GAMP5-oriented documentation needs
- Audit-trail and user-related topics
- 21 CFR Part 11 requirements and documentation support
Please describe which certificates, templates or documentation requirements are relevant for your system or project.
Service levels available on request
Choose the service structure that fits your bioreactor operation: from yearly maintenance to software-upgrade support and guaranteed response times.
Exact service-level scope, discount level, availability and response times are discussed individually and depend on system type, location and support requirements.
Engineering packages for larger bioreactor projects
Large bioreactor projects often start long before a purchase decision is possible. For early-stage projects, funding applications, consortium planning or CAPEX discussions, bbi-biotech can provide defined basic engineering packages that turn an idea into usable technical planning documents.
These packages do not require the final system to be built by bbi-biotech. They are intended to give customers, project partners and decision-makers a supplier-independent basis for the next planning step.
Basic Engineering
Turn an early project idea into a technical starting point
When the realization of a larger project is still uncertain, a structured basic engineering step can help define the process goals, system boundaries, technical assumptions and open decisions before a full quotation is possible.
A practical first step for funding-driven, consortium-based or CAPEX-relevant projects before formal project commitment.
- Technical project framing
- Process and scale assumptions
- Open-point definition
URS development
Create requirements that can be discussed beyond one supplier
bbi-biotech can support the preparation of user requirement specifications for larger bioreactor projects, including process needs, automation expectations, interfaces, documentation requirements and operating conditions.
A well-prepared URS helps align users, engineering teams, procurement, funders and potential suppliers.
- System requirements
- Process requirements
- Documentation requirements
CAPEX support
Build a realistic basis for budgets and funding decisions
For projects that are not yet approved, bbi-biotech can prepare budgetary equipment concepts and CAPEX-oriented calculations to support internal approvals, grant applications or consortium discussions.
This helps avoid unrealistic early budgets before a responsible commercial quotation can be prepared.
- Budgetary equipment concept
- CAPEX estimate support
- Funding discussion input
Feasibility review
Check whether the intended concept is technically plausible
A feasibility review can assess whether the planned scale, vessel concept, automation approach, utilities, process assumptions or integration requirements are realistic before the project moves further into planning.
Useful when technical feasibility must be clarified before committing time, budget or partners.
- Concept plausibility
- Technical limitations
- Risk and gap review
P&ID basis
Define the process logic before detailed engineering starts
For larger systems, bbi-biotech can prepare or support early P&ID work to clarify process connections, instrumentation, utility interfaces, valve logic, transfer routes and automation-relevant system elements.
A preliminary P&ID gives engineering teams and project partners a clearer basis for discussion.
- Process connections
- Instrumentation logic
- Utility interfaces
Room and layout planning
Understand how the system fits into the facility concept
Room-planning support can help clarify equipment footprint, access routes, utilities, installation constraints, operator access, maintenance access and integration into an existing or planned facility.
This reduces the risk of space, utility or access problems becoming visible too late in the planning phase.
- Footprint planning
- Access requirements
- Facility interfaces
Basic engineering packages are defined individually and are especially useful when larger bioreactor projects need reliable planning documents before supplier selection, funding approval or final project realization is clear.
Bioprocessing trainings and lectures
Bioreactor knowledge is often built through years of real projects, installations, service cases, process discussions and technical decisions.
bbi-biotech offers customer-specific trainings, technical lectures and knowledge-transfer formats for teams that want to understand bioreactor operation, automation, sampling, scale-up or lifecycle decisions more deeply. These formats are especially useful for start-ups, young technical teams, project groups and growing organizations that want to benefit from proven bioreactor experience before repeating avoidable trial-and-error cycles.
Practical system training
Help operators work more confidently with their system
Customer-specific training can be prepared around the installed system, user group, operating routines and real questions from the customer’s team — from daily handling to alarms, trends, pumps, sensors or controller use.
Useful for operators, new users or teams taking over an existing bioreactor system.
- System-specific operation
- Operator questions
- Practical routines
xCUBIO and bioprocess automation
Make automation logic easier to understand, use and discuss
For xCUBIO systems, training can focus on user interface handling, sequence logic, recipes, automated process steps, alarms, trends or customer-specific automation workflows depending on the installed system.
Useful when automated functions should become clearer, safer and easier to review internally.
- xCUBIO operation
- Sequence understanding
- Automation workflows
Process and application lectures
Connect equipment decisions with biological process goals
Application-specific lectures can address process-related topics such as microbial fermentation, cell culture, photobioreactors, sampling strategy, feeding concepts, sensor use, scale-up considerations or equipment configuration.
Useful for teams that need to understand not only how a system works, but why certain technical decisions matter.
- Application context
- Feeding concepts
- Scale-up considerations
Sterilization, CIP and batch routines
Build clearer routines before, during and between batches
Training can address preparation steps, sterilization-related operation, CIP-related workflows, cleaning logic, operator tasks, batch readiness and system-specific routines for reproducible operation.
Useful when reliable operation depends on clear responsibilities and repeatable procedures.
- Sterilization routines
- CIP-related workflows
- Batch preparation
Bioreactor experience transfer
Learn from long-term bioreactor, service and project experience
Experienced bbi-biotech specialists can provide lectures or workshops on selected topics from bioreactor development, process engineering, installation, commissioning, service, retrofit, automation and lifecycle support.
Especially valuable for start-ups and young technical teams that want to understand what has already been tried, what worked and which pitfalls should be avoided.
- Lessons learned
- Retrofit and lifecycle topics
- Project decision support
Sampling and sterile handling
Understand sampling decisions and process bottlenecks
Training can address sterile sampling concepts, manual and automated sampling strategies, sample routing, filtration questions, dead volume, contamination risks and practical handling around bioreactor sampling.
Useful when teams need reliable samples without compromising sterility, process integrity or daily usability.
- Sterile sampling concepts
- Contamination risk awareness
- Manual and automated options
Training and lecture content is defined individually according to the system, application, audience and technical goal. Formats can be arranged remote, on-site or at bbi-biotech depending on scope.
Tell us about your bioreactor or fermenter
Whether you need service for an existing system, recurring maintenance, spare parts, consumables, documentation support or a new bioreactor project, we will route your enquiry to the right team and next step.
I need service for an existing system – For running bioreactors, maintenance and lifecycle support
Use this route for preventive maintenance, repair assessment, service planning, documentation-related service topics, retrofit questions or support for xCUBIO, bbi-biotech or suitable legacy stainless-steel systems.
I need spare parts or consumables – For standard items, wear parts, accessories and compatibility questions
Use this route for spare parts, consumables, tubing, seals, membranes, O-rings, filters, sampling accessories, vessel-side components or unclear compatibility with an existing system.
I am planning a bioreactor project – For new systems, quotations, scale-up concepts and technical feasibility
Use this route if you are planning a new bioreactor, comparing vessel concepts, defining automation options, preparing a quotation request or discussing process and scale-up requirements.
Direct contact to Berlin head office
+49 (0)30 221 800 10
info@bbi-biotech.com
bbi-biotech GmbH
Landsberger Str. 259
12623 Berlin