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Autosampler multiSAM


Aseptic Sampling and Flexible Sample Handling with bioPROBE and multiSAM

multiSAM is as flexible as the possibilities in modern biotechnology. multiSAM can be used for sampling from one bioreactor with bioPROBE single and for parallel sampling with bioPROBE quad.

With the help of Addons und Extension Packs multiSAM can be extended in its functionalities and customized to every application.

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multiSAM Extension Packs

Extension Pack Details
Standard Vials 13 ml Open For the storage of samples in 96 Standard vials 13 ml (100 x 16 mm) of various manufacturers
Standard Multi-Well For the storage of samples in 4 Microtiter plates in 96-Deep-Well-Format or 48-Deep-Well-Format (2 ml, 5 ml, 10 ml) of various manufacturers. Up to 384 samples without changing of plates
Standard Falcon 50 ml Open For the storage of samples in 50ml-Falcon vials without caps of various manufacturers
Standard Falcon 50 ml Septum For the storage of samples in 50ml-Falcon-Tubes with pre-slit septum or septum and ventilation membrane, for example TubeSpin® Bioreactor 50 with Septum by TPP or 50ml SeptaVent™ by Marin Scientifc
Standard Falcon 15 ml Open For the storage of samples in 96x 15ml Falcon vials without caps of various manufacturers
Standard Falcon 15 ml Septum For the storage of samples in 96x 15ml Falcon vials with pre-slit septum or septum and ventilation membrane, for example Cross Cut Septa Caps w/ 15 mL Falcon™ Tubes by syringalabsupplies
Standard Bioprocess Bags For the storage of samples in single-use bioprocess bags (50 ml, 100 ml, 200 ml) of various manufacturers
Standard Bioprocess Bags XL For the storage of samples in single-use bioprocess bags (200 ml, 500 ml, 1000 ml) of various manufacturers

Customized Extension Packs can be manufactured for every vial type with or withour septum. Contact us for more details!

multiSAM is not only for cell-containing samples. It can also be used directly for a safe pressure filtration. The superiour design and the use of single-use filters assures:

No BioFouling!

No cross contaminations!

No distortion of the analysis!


Extension Pack Details
MTP Filtration Filtration with 96-Well-Filterplates of various manufacturers (Pall, GE, Millipore, ThermoFisher, Ahn-Bio, etc..). Suitable for the filtration of uncritical media in small volumes.
Chromafil Cartridge Filtration 3ml Filtration with Chromafil 3ml filter cartridges of Macherey-Nagel. Suitable for the filtration of uncritical media.
Chromafil Cartridge Filtration 6ml Filtration with Chromafil 3ml filter cartridges of Macherey-Nagel. Suitable for the filtration of uncritical media in larger volume.
MediaKap Filtration Filtration with MediaKap-2 and MediaKap-5 hollow fiber filter cartridges by spectrumlabs. Suitable for the filtration of critical and high-concentrated media.
Extension Pack Details
Peltier Starter For the storage and cooling of samples in Eppendorf Thermostat C coolers. Suitable for vials with or without septum. Volumes from 2ml to 50 ml. Mixed configurations possible.
Water Bath Standard For the storage and cooling of samples. With 4 exchangable sampling inlays. Possibility to be combined with Filtration Extension Packs.

Most Extension Packs for multiSAM can be used with bioPROBE single and bioPROBE quad. The Quad Extension Packs consist of a customized canula holder for 4 canulas and a corresponding cleaning station, that can be changed by the user within minutes

Extension Pack Details
Quad for Standard Vials 13 ml For the combination with all Extension Packs for 13 ml vials
Quad for MTP 96 For the combination of bioPROBE quad with multiSAM and an Extension Pack for MTP-96-Deep-Wellplates
Quad for MTP 48 For the combination of bioPROBE quad with multiSAM and an Extension Pack for MTP-48-Deep-Wellplates
Quad for Falcon 50 ml For the combination of bioPROBE quad with multiSAM and an Extension Pack for 50 ml Falcon vials
Quad for Bioprocess Bags For the combination of bioPROBE quad with multiSAM and an Extension Pack Bioprocess Bags.
Quad for Bioprocess Bags XL For the combination of bioPROBE quad with multiSAM and an Extension Pack Bioprocess Bags XL.
Extension Pack Details
Safety Housing Additional safety housing. Automatic stop of all moving parts when opened.
Sterile Housing UV Sterile safety housing for bioPROBE single + multiSAM or bioPROBE quad und multiSAM. UV sterilization and air circulation allow sampling in a 100% sterile environment.
Laminar-Flow Extra sterility measurement for canulas in-between samples in gmp environments
GMP-Audit-Trail GMP conform audit trail according to FDA 21 CFR 11 and EU GMP Annex 11
OPC Functionality Control bioPROBE and multiSAM via OPC UA protocol. Communication with external programs like matlab or SCADA systems.
Extension Pack Details
MACSQuant Automated Flowcytometry with MACSQuant™ by Miltenyi Biotec GmbH
Vi-Cell XR Automated cell-counting with Vi-CELL™ XR by Beckman Coulter
Customized Advanced sample preparation with external liquid handling platforms. Integration of dilution, mixing and other sample preparation modules. Customized solutions for your PAT process and your analyzers.

multiSAM product video

Click to play a video of multiSAM with bioPROBE single equipped with the Extension Pack Peltier Starter.